EMG-driven Muscle Activations Tune Post-Stroke Computed Muscle Control Simulations

INTRODUCTION OpenSim is an open-source musculoskeletal modeling program that uses computed muscle control (CMC) to estimate muscle excitation patterns during a particular task [1,2]. CMC determines the excitations by minimizing the weighted sum of muscle forces while reproducing the desired kinematics. With this approach, estimates of muscle excitations in populations with known muscle activation impairment (i.e., stroke) may not be accurate without proper input signals representative of the neural impairment.